Addiction (whether to prescription drugs, alcohol, tobacco, gambling) and overdosing are two major plagues of modern society.   Drug overdosing causes c. 50,000 deaths per year in the USA, and around. 2.6 million people suffer chronically from Opioid Use Disorder worldwide.

The preferred option for treating Opioid Use Disorder is the API Buprenorphine, which is often combined with opioid antagonists such as Naloxone.   However the production of these molecules involve challenging chemistry leading to high costs, the formation of toxic by-products and significant inefficiencies in their supply chain

River Stone has developed a synthetic biology route to the manufacture of these APIs which removes the challenging chemistry, allowing for a much simpler, and much more affordable, production process.

If you are currently purchasing Buprenorphine, Naloxone and Naltrexone APIs, then we would be interested to talk and see if we can provide you an attractive alternative to your current sources.