“We simplify complex, expensive and environmentally
challenging supply chains for small molecule APIs
using the power of synthetic biology in combination
with synthetic chemistry”

Esben Halkjær Hansen, SVP R&D

A Superior R&D Platform for Future Green Chemistry

An enzyme is a protein that can catalyze a chemical reaction. The River Stone technology uses enzymes to replace difficult chemistry.

Some enzymes can be used outside living organisms, simply by mixing enzyme with the substrate you need to convert.

Some enzymes work best inside a living organism and sometimes several enzymes are needed to act one after each other to make the desired product. In this case the enzymes are expressed in a living microorganism which can be grown in large fermentation tanks to produce the product. To a large extent like brewing beer.

From idea to product

In order to make an enzymatic process into a viable commercial product, the process has to be scaled in order to product the kilos or tons needed.

River Stone has strong capabilities within microbial fermentation and well as an experienced down stream processing team developing and optimizing processes to purify the final products.

Leveraging Our Platform

River Stone Biotech has established a strong IP portfolio and a versatile production platform that can be extended well beyond any single product class. By combining engineered biosynthesis with selective chemical upgrading, we enable differentiated, cost-effective routes to a broad range of specialty molecules.

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These include complex small molecules, fatty acid derivatives, and key intermediates/precursors and final APIs for pharmaceutical and non-pharma applications. A core advantage of our approach is consistent control of stereochemistry, delivering products with the right chirality and robust quality at scalable manufacturing volumes.